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How Long Does Narcan Make You Sick?

Wondering how long Narcan makes you sick? The withdrawal symptoms usually start within minutes and last a few hours. This article covers why this happens, how long it lasts, and what to expect.

Key Takeaways

  • Narcan (naloxone) causes temporary sickness due to the rapid onset of opioid withdrawal symptoms after reversing an overdose.
  • The duration of withdrawal symptoms usually lasts from 30 minutes to 2 hours, influenced by factors such as opioid tolerance, type, and administration method.
  • While withdrawal symptoms can be distressing, they are not life-threatening and typically resolve quickly, with proper medical monitoring recommended.

What is Narcan, and why does it cause sickness?

Narcan, or naloxone hydrochloride, is a fast-acting opioid antagonist specifically designed to counteract the life-threatening effects of an opioid overdose. When someone experiences an opioid overdose, their breathing can slow or stop, leading to fatal consequences. Narcan works by quickly displacing opioids from the receptors in the brain, effectively reversing the overdose and restoring normal breathing.

However, this life-saving reversal comes with a price. The abrupt displacement of opioids by Narcan can trigger acute withdrawal symptoms. This sudden shift from an opioid-induced state to withdrawal can cause a variety of unpleasant and distressing symptoms, often perceived as “sickness” by those experiencing it. These symptoms are not side effects of Narcan itself but are instead a direct result of the rapid opioid withdrawal it induces.

Understanding that this “sickness” is a natural consequence of how Narcan works can help prepare those administering the drug and those receiving it. While the symptoms can be quite uncomfortable, they are a small price to pay for the life-saving benefits that Narcan offers.

An illustration showing Narcan nasal spray being held with a blurred background of an emergency setting.

How long does Narcan make you feel sick?

The duration of sickness after Narcan administration can vary, but most withdrawal symptoms start within minutes and peak within 30 to 90 minutes. Narcan itself has a short half-life, typically lasting between 30 to 90 minutes. This means that while Narcan works quickly to reverse an opioid overdose, its effects are also short-lived, and the withdrawal symptoms it triggers are generally short-term.

However, the severity and duration of these symptoms can depend on several factors. The amount of opioids in the person’s system and their history of opioid use play significant roles in how long they will feel sick. For instance, someone with a long history of heavy opioid use may experience more intense and prolonged withdrawal symptoms compared to someone with a shorter or lighter use history, including the effects of opioids.

While the immediate effects of naloxone are typically short-lived, it is essential to monitor the individual for a while after administration. This is because the opioids in their system might outlast the effects of naloxone, leading to potential re-narcotization and a return of overdose symptoms.

What symptoms does Narcan commonly cause?

Common symptoms following Narcan administration include:

  • Nausea
  • Vomiting
  • Body aches
  • Sweating
  • Anxiety
  • Restlessness
  • Rapid heart rate
  • Diarrhea

These symptoms mirror those of opioid withdrawal and can be quite uncomfortable, but it is important to note that they are not direct side effects of Narcan itself.

These withdrawal symptoms occur because Narcan displaces opioids from the brain receptors, abruptly cutting off the opioid effects and triggering withdrawal. This sudden change can be distressing, but it is not life-threatening. Understanding these symptoms can help caregivers and medical personnel provide appropriate support and reassurance to the affected individual.

While experiencing these symptoms can be alarming, knowing that they are temporary and a sign that Narcan is effectively reversing the overdose can provide some comfort. Most symptoms resolve within a few hours, especially with proper medical monitoring and supportive care.

A visual representation of common symptoms caused by Narcan, with icons for nausea and dizziness.

Factors that influence how sick you feel after Narcan

Several factors can influence the intensity and duration of sickness after Narcan administration. One of the primary factors is the individual’s opioid tolerance level and history of chronic use. Those with a higher tolerance or longer history of opioid use are likely to experience more severe withdrawal symptoms.

The type of opioid involved also plays a significant role. Stronger opioids like fentanyl can result in more intense withdrawal symptoms compared to opioids like heroin. Additionally, the half-life of the opioid can affect how long the withdrawal symptoms last after Narcan administration.

The dose and route of Narcan administration also matter. Intranasal administration, such as with a naloxone hydrochloride spray or a naloxone nasal spray, might produce different effects compared to intramuscular administration. Furthermore, whether follow-up care or additional opioid use occurs after a dose of naloxone administration can greatly influence how sick an individual feels.

How to manage sickness after Narcan administration

Managing sickness after Narcan administration primarily involves:

  • Supportive care and medical monitoring to stabilize the individual’s condition.
  • Managing symptoms like nausea and vomiting with hydration and anti-nausea medication.
  • Providing rest and a calm environment to help alleviate anxiety and restlessness.

One of the critical points to remember is that re-administering opioids after Narcan can be extremely dangerous. It can lead to a reverse opioid overdose, putting the individual at significant risk. Therefore, it is essential to resist the urge to give any opioids and instead focus on supportive care and monitoring until the effects of Narcan wear off.

Proper medical monitoring is vital, as the person might need multiple doses of Narcan if the opioids in their system outlast the effects of the first dose or require a second dose. Emergency medical professionals can provide the necessary care to ensure the individual’s safety during this opioid emergency.

A person receiving medical assistance after Narcan administration, with a focus on care rather than brand names.

When to seek medical attention

Knowing when to seek medical attention after Narcan administration is crucial:

  • Severe withdrawal symptoms such as intense body aches, fever, and persistent vomiting require immediate medical attention.
  • Even if the person appears to recover, it is essential to monitor them closely.
  • The effects of Narcan may wear off before the opioids are fully eliminated from their system.

Always call 911 immediately after administering Narcan in the following situations:

  • The individual does not regain consciousness.
  • The individual shows signs of severe symptoms like difficulty breathing or extreme dizziness.
  • There are persistent or worsening side effects, such as ongoing heart problems.

These situations warrant immediate medical evaluation.

In cases where the individual does not respond or regain consciousness within a few minutes of Narcan administration, seek emergency help without delay. Timely medical intervention can be life-saving in such situations.

Can Narcan cause long-term side effects?

Narcan does not cause long-term sickness or organ damage. It is designed to rapidly reverse the effects of an opioid overdose without causing lasting harm. However, rare allergic reactions can occur, and it is essential to seek proper medical follow-up if any prolonged symptoms arise.

Any prolonged symptoms after Narcan administration are more likely due to underlying health or substance use issues rather than the drug itself. Ensuring appropriate medical care and addressing any underlying conditions can help manage these symptoms effectively.

Is feeling sick after Narcan a sign of addiction?

Feeling sick after Narcan administration is not a sign of addiction; it is a sign of opioid withdrawal. Severe withdrawal symptoms may suggest opioid dependence or addiction, but the sickness caused by Narcan itself is due to the abrupt withdrawal it triggers. Symptoms like nausea and agitation are common during opioid withdrawal and do not indicate addiction.

Opioid use disorder is characterized by a physical dependence on opioids, and recognizing the signs of this disorder is crucial for seeking appropriate treatment. Narcan is designed to counteract opioid effects and does not lead to addiction or dependency itself. Opioid drugs can also play a role in the treatment process.

Encouraging those who experience severe withdrawal symptoms to seek professional help can be a vital step toward sustained recovery. Treatment options for opioid use disorder can provide the necessary support for pain relief to overcome opioid addiction and prevent future overdoses.

Bottom Line: What to remember about Narcan and sickness

Narcan-induced sickness is short-term and results from sudden opioid withdrawal. While the symptoms can be uncomfortable, they typically resolve within a few hours and should be medically monitored to ensure the individual’s safety.

It is crucial to remember that Narcan is a life-saving medication and should always be used in suspected opioid overdose situations, giving naloxone kits. The temporary discomfort caused by withdrawal symptoms is a small price to pay for the opportunity to save a life.

FAQs about Narcan side effects and the duration of sickness

Can Narcan make someone throw up?

Yes, Narcan can induce nausea and vomiting as common withdrawal symptoms following its administration.

How long do withdrawal symptoms last after Narcan?

Withdrawal symptoms after Narcan typically last between 2 to 4 hours, but individual experiences may vary.

Can you overdose on Narcan?

It is not possible to overdose on Narcan; however, repeated doses may lead to intensified withdrawal symptoms.

Is it safe to give Narcan even if unsure?

It is safe to administer Narcan even if you are unsure about opioid presence, as there are no harmful effects if opioids are not involved. Acting quickly in suspected opioid overdoses can save lives.

What should I do if someone does not respond to Narcan?

If someone does not respond to Narcan, it is crucial to call 911 immediately for emergency medical assistance. Prompt action can save the person's life.

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